According to WMC5 News, the top five red Powerball numbers drawn in the past 10 years are 20, 37, 2, 31, and 35. The number 20 has been drawn as the red Powerball at least 50 times in the past decade.

When it comes to choosing the white balls, the number 42 has been drawn the most often followed by 16, 35, 26, and 19.

However, don't expect to be winner if you use some or all of those numbers. Whether you play a Quick pick or use you favorite numbers, it a game of luck unless you have millions to blow on tickets. CNBC reports that you would have to play every number combination to guarantee a win. That equates to over 175,223,510 tickets that would set you back a cool $350 million.

Powerball numbers are drawn at 11 p.m. ET on Wednesday night and Saturday nights. Buy your Powerball ticket at least one hour before the drawing on Wednesday if you want a chance to win the $400 million jackpot prize.

What's the first thing you would do with your millions if you win the Powerball jackpot on Wednesday night?