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Differential effects of estrogen/androgen on the prevention of nonalcoholic fatty liver disease in the male rat [Research Articles]

2013-02-15 22:44:00 (читать в оригинале)

It is important to clarify the distinct contributions of estrogen/estrogen receptor (ER) and androgen/androgen receptor (AR) signaling and their reciprocal effects on the regulation of hepatic lipid homeostasis. We studied the molecular mechanisms underlying the preventive effects of estradiol (E2), dihydrotestosterone (DHT), or E2+DHT on high-fat diet-induced nonalcoholic fatty liver disease (NAFLD) in an orchidectomized Sprague-Dawley (SD) rat model. E2 is shown to be associated with decreased fatty acid synthesis in hepatic zone 3-specific manner by increasing the phosphorylation of acetyl coenzyme-A carboxylase via an ERα-mediated pathway. DHT is shown to be associated with decreased lipid accumulation and cholesterol synthesis in a hepatic zone 1-specific manner by increasing ex...







Pediatrician schedule: Boca Raton 83,280
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Pediatrician schedule: Boynton Beach 69,654
Pediatrician schedule: Bradenton 53,973
Pediatrician schedule: Brandon, FL 90,833
Pediatrician schedule: Brent, FL 22,845
Pediatrician schedule: Broadview Park 7,278
Pediatrician schedule: Brooksville, FL 8,267
Pediatrician schedule: Brownsville, FL 15,634
Pediatrician schedule: Butler Beach 6,265
Pediatrician schedule: Callaway, FL 13,972
Pediatrician schedule: Cantonment 44,893
Pediatrician schedule: Cape Canaveral 10,081
Pediatrician schedule: Cape Coral, FL 154,202
Pediatrician schedule: Carol City 64,569
Pediatrician schedule: Casselberry 24,792
Pediatrician schedule: Central Pasco 69,995
Pediatrician schedule: Central Volusia 24,310
Pediatrician schedule: Century Village 8,483
Pediatrician schedule: Cheval 8,864
Pediatrician schedule: Citrus Park 23,585
Pediatrician schedule: Citrus Park-Fern Lake, FL 117,103
Pediatrician schedule: Citrus Ridge 14,195
Pediatrician schedule: Clearwater, FL 106,081
Pediatrician schedule: Clermont, FL 13,252
Pediatrician schedule: Clewiston 7,107
Pediatrician schedule: Cocoa 16,538
Pediatrician schedule: Cocoa Beach 11,862
Pediatrician schedule: Cocoa West 7,806
Pediatrician schedule: Coconut Creek 50,544
Pediatrician schedule: Collier Manor-Cresthaven 8,287
Pediatrician schedule: Combee Settlement 6,422
Pediatrician schedule: Conway, FL 16,998
Pediatrician schedule: Cooper City 29,585
Pediatrician schedule: Coral Gables 44,425
Pediatrician schedule: Coral Springs, FL 126,518
Pediatrician schedule: Coral Terrace 26,482
Pediatrician schedule: Country Club, FL 39,441
Pediatrician schedule: Country Walk 11,571
Pediatrician schedule: Crestview, FL 19,868
Pediatrician schedule: Cutler Ridge 26,918
Pediatrician schedule: Cutler, FL 18,889
Pediatrician schedule: Cypress Gardens 10,449
Pediatrician schedule: Cypress Lake 15,915
Pediatrician schedule: Dade City 7,190
Pediatrician schedule: Dania Beach 21,477
Pediatrician schedule: Davie 91,729
Pediatrician schedule: Daytona Beach 63,795
Pediatrician schedule: De Bary 16,200


A common variant highly associated with plasma VEGFA levels also contributes to the variation of both LDL-C and HDL-C [Patient-Oriented and Epidemiological Research]
White Rings: Arcus Lipoides
Diacylglycerol kinase inhibitor R59022 attenuates conjugated linoleic acid-mediated inflammation in human adipocytes [Research Articles]
The shape and free energy of a lipid bilayer surrounding a membrane inclusion.
Monotopic topology is required for lipid droplet targeting of ancient ubiquitous protein 1 [Research Articles]
Influence of oil phase concentration on droplet size distribution and stability of oil‐in‐water emulsions
Caspase-1 deficiency in mice reduces intestinal triglyceride absorption and hepatic triglyceride secretion [Research Articles]
Eur. J. Lipid Sci. Technol. 1/2013
LCAT deficiency in mice is associated with a diminished adrenal glucocorticoid function [Research Articles]
Non-HDL cholesterol, ApoB and LDL particle concentration in coronary heart disease risk prediction and treatment

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Is there a link between alcohol consumption and metabolic syndrome?

2013-02-15 22:44:00 (читать в оригинале)

Clinical Lipidology , February 2013, Vol. 8, No. 1, Pages 5-8. (Source: Future Medicine: Clinical Lipidology)







Pediatrician schedule: Boca Raton 83,280
Pediatrician schedule: Bonita Springs 42,874
Pediatrician schedule: Boyette 6,874
Pediatrician schedule: Boynton Beach 69,654
Pediatrician schedule: Bradenton 53,973
Pediatrician schedule: Brandon, FL 90,833
Pediatrician schedule: Brent, FL 22,845
Pediatrician schedule: Broadview Park 7,278
Pediatrician schedule: Brooksville, FL 8,267
Pediatrician schedule: Brownsville, FL 15,634
Pediatrician schedule: Butler Beach 6,265
Pediatrician schedule: Callaway, FL 13,972
Pediatrician schedule: Cantonment 44,893
Pediatrician schedule: Cape Canaveral 10,081
Pediatrician schedule: Cape Coral, FL 154,202
Pediatrician schedule: Carol City 64,569
Pediatrician schedule: Casselberry 24,792
Pediatrician schedule: Central Pasco 69,995
Pediatrician schedule: Central Volusia 24,310
Pediatrician schedule: Century Village 8,483
Pediatrician schedule: Cheval 8,864
Pediatrician schedule: Citrus Park 23,585
Pediatrician schedule: Citrus Park-Fern Lake, FL 117,103
Pediatrician schedule: Citrus Ridge 14,195
Pediatrician schedule: Clearwater, FL 106,081
Pediatrician schedule: Clermont, FL 13,252
Pediatrician schedule: Clewiston 7,107
Pediatrician schedule: Cocoa 16,538
Pediatrician schedule: Cocoa Beach 11,862
Pediatrician schedule: Cocoa West 7,806
Pediatrician schedule: Coconut Creek 50,544
Pediatrician schedule: Collier Manor-Cresthaven 8,287
Pediatrician schedule: Combee Settlement 6,422
Pediatrician schedule: Conway, FL 16,998
Pediatrician schedule: Cooper City 29,585
Pediatrician schedule: Coral Gables 44,425
Pediatrician schedule: Coral Springs, FL 126,518
Pediatrician schedule: Coral Terrace 26,482
Pediatrician schedule: Country Club, FL 39,441
Pediatrician schedule: Country Walk 11,571
Pediatrician schedule: Crestview, FL 19,868
Pediatrician schedule: Cutler Ridge 26,918
Pediatrician schedule: Cutler, FL 18,889
Pediatrician schedule: Cypress Gardens 10,449
Pediatrician schedule: Cypress Lake 15,915
Pediatrician schedule: Dade City 7,190
Pediatrician schedule: Dania Beach 21,477
Pediatrician schedule: Davie 91,729
Pediatrician schedule: Daytona Beach 63,795
Pediatrician schedule: De Bary 16,200


Lipid metabolism, immunity and metabolic diseases
Eur. J. Lipid Sci. Technol. 1/2013
LCAT deficiency in mice is associated with a diminished adrenal glucocorticoid function [Research Articles]
The molecular basis of ceramide-1-phosphate recognition by C2 domains [Research Articles]
Invariant NKT cell serves as a novel therapeutic target for control of obesity
Non-HDL cholesterol, ApoB and LDL particle concentration in coronary heart disease risk prediction and treatment
Fasting regulates FSP27 expression in the liver [Commentary]
Cobalt carbonyl complexes as probes for alkyne-tagged lipids [Methods]
Effect of talc and water addition on olive oil quality and antioxidants
The combined effects of genetic variation in the SIRT1 gene and dietary intake of n-3 and n-6 polyunsaturated fatty acids on serum LDL-C and HDL-C levels: a population based study

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Lipoprotein metabolism in patients with type 1 diabetes under intensive insulin treatment

2013-02-15 22:44:00 (читать в оригинале)

Conclusion:T1DM patients under intensive insulin treatment but with poor glycemic control had lower LDL-cholesterol with higher LDE plasma clearance, indicating that LDL plasma removal was even more efficient than in controls. Furthermore, HDL-cholesterol and triglycerides, cholesterol esterification and transfer of lipids to HDL, an important step in reverse cholesterol transport, were all normal. Coexistence of high glycemia levels with normal intravascular lipid metabolism may be related to differences in exogenous insulin bioavailabity and different insulin mechanisms of action on glucose and lipids. Those findings may have important implications for prevention of macrovascular disease by intensive insulin treatment. (Source: Lipids in Health and Disease)







Pediatrician schedule: Boca Raton 83,280
Pediatrician schedule: Bonita Springs 42,874
Pediatrician schedule: Boyette 6,874
Pediatrician schedule: Boynton Beach 69,654
Pediatrician schedule: Bradenton 53,973
Pediatrician schedule: Brandon, FL 90,833
Pediatrician schedule: Brent, FL 22,845
Pediatrician schedule: Broadview Park 7,278
Pediatrician schedule: Brooksville, FL 8,267
Pediatrician schedule: Brownsville, FL 15,634
Pediatrician schedule: Butler Beach 6,265
Pediatrician schedule: Callaway, FL 13,972
Pediatrician schedule: Cantonment 44,893
Pediatrician schedule: Cape Canaveral 10,081
Pediatrician schedule: Cape Coral, FL 154,202
Pediatrician schedule: Carol City 64,569
Pediatrician schedule: Casselberry 24,792
Pediatrician schedule: Central Pasco 69,995
Pediatrician schedule: Central Volusia 24,310
Pediatrician schedule: Century Village 8,483
Pediatrician schedule: Cheval 8,864
Pediatrician schedule: Citrus Park 23,585
Pediatrician schedule: Citrus Park-Fern Lake, FL 117,103
Pediatrician schedule: Citrus Ridge 14,195
Pediatrician schedule: Clearwater, FL 106,081
Pediatrician schedule: Clermont, FL 13,252
Pediatrician schedule: Clewiston 7,107
Pediatrician schedule: Cocoa 16,538
Pediatrician schedule: Cocoa Beach 11,862
Pediatrician schedule: Cocoa West 7,806
Pediatrician schedule: Coconut Creek 50,544
Pediatrician schedule: Collier Manor-Cresthaven 8,287
Pediatrician schedule: Combee Settlement 6,422
Pediatrician schedule: Conway, FL 16,998
Pediatrician schedule: Cooper City 29,585
Pediatrician schedule: Coral Gables 44,425
Pediatrician schedule: Coral Springs, FL 126,518
Pediatrician schedule: Coral Terrace 26,482
Pediatrician schedule: Country Club, FL 39,441
Pediatrician schedule: Country Walk 11,571
Pediatrician schedule: Crestview, FL 19,868
Pediatrician schedule: Cutler Ridge 26,918
Pediatrician schedule: Cutler, FL 18,889
Pediatrician schedule: Cypress Gardens 10,449
Pediatrician schedule: Cypress Lake 15,915
Pediatrician schedule: Dade City 7,190
Pediatrician schedule: Dania Beach 21,477
Pediatrician schedule: Davie 91,729
Pediatrician schedule: Daytona Beach 63,795
Pediatrician schedule: De Bary 16,200


Monotopic topology is required for lipid droplet targeting of ancient ubiquitous protein 1 [Research Articles]
Invariant NKT cell serves as a novel therapeutic target for control of obesity
Adipose tissue arachidonic acid content is associated with the expression of 5-lipoxygenase in atherosclerotic plaques
Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice [Research Articles]
Eur. J. Lipid Sci. Technol. 1/2013
Differential effects of estrogen/androgen on the prevention of nonalcoholic fatty liver disease in the male rat [Research Articles]
A common variant highly associated with plasma VEGFA levels also contributes to the variation of both LDL-C and HDL-C [Patient-Oriented and Epidemiological Research]
LCAT deficiency in mice is associated with a diminished adrenal glucocorticoid function [Research Articles]
Eur. J. Lipid Sci. Technol. 2/2013
Novel common and rare genetic determinants of paraoxonase activity: FTO, SERPINA12, and ITGAL [Patient-Oriented and Epidemiological Research]

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Impact of extruded flaxseed meal supplemented diet on growth performance, oxidative stability and quality of broiler meat and meat products

2013-02-15 22:44:00 (читать в оригинале)

This study was intended to explore the effect of extruded flaxseed meal supplemented diet on broiler growth performance, oxidative stability and organoleptic characteristics of broiler meat and meat products. 120 (day old) broiler chicks were randomly allotted to 12 experimental groups and fed on diets containing extruded flaxseed meal at 0, 5, 10 and 15%. The supplementation of extruded flaxseed in the diet decreases the body weight gain, feed intake and increased feed conversion ratio (FCR) values of broilers. The antioxidant enzymes were strongly influenced by different levels of extruded flaxseed supplementation among treatments. The TBARS assay revealed that maximum malondialdehyde were produced in T3 containing highest extruded flaxseed level (15%) and minimum malondialdehyde were pr...







Pediatrician schedule: Boca Raton 83,280
Pediatrician schedule: Bonita Springs 42,874
Pediatrician schedule: Boyette 6,874
Pediatrician schedule: Boynton Beach 69,654
Pediatrician schedule: Bradenton 53,973
Pediatrician schedule: Brandon, FL 90,833
Pediatrician schedule: Brent, FL 22,845
Pediatrician schedule: Broadview Park 7,278
Pediatrician schedule: Brooksville, FL 8,267
Pediatrician schedule: Brownsville, FL 15,634
Pediatrician schedule: Butler Beach 6,265
Pediatrician schedule: Callaway, FL 13,972
Pediatrician schedule: Cantonment 44,893
Pediatrician schedule: Cape Canaveral 10,081
Pediatrician schedule: Cape Coral, FL 154,202
Pediatrician schedule: Carol City 64,569
Pediatrician schedule: Casselberry 24,792
Pediatrician schedule: Central Pasco 69,995
Pediatrician schedule: Central Volusia 24,310
Pediatrician schedule: Century Village 8,483
Pediatrician schedule: Cheval 8,864
Pediatrician schedule: Citrus Park 23,585
Pediatrician schedule: Citrus Park-Fern Lake, FL 117,103
Pediatrician schedule: Citrus Ridge 14,195
Pediatrician schedule: Clearwater, FL 106,081
Pediatrician schedule: Clermont, FL 13,252
Pediatrician schedule: Clewiston 7,107
Pediatrician schedule: Cocoa 16,538
Pediatrician schedule: Cocoa Beach 11,862
Pediatrician schedule: Cocoa West 7,806
Pediatrician schedule: Coconut Creek 50,544
Pediatrician schedule: Collier Manor-Cresthaven 8,287
Pediatrician schedule: Combee Settlement 6,422
Pediatrician schedule: Conway, FL 16,998
Pediatrician schedule: Cooper City 29,585
Pediatrician schedule: Coral Gables 44,425
Pediatrician schedule: Coral Springs, FL 126,518
Pediatrician schedule: Coral Terrace 26,482
Pediatrician schedule: Country Club, FL 39,441
Pediatrician schedule: Country Walk 11,571
Pediatrician schedule: Crestview, FL 19,868
Pediatrician schedule: Cutler Ridge 26,918
Pediatrician schedule: Cutler, FL 18,889
Pediatrician schedule: Cypress Gardens 10,449
Pediatrician schedule: Cypress Lake 15,915
Pediatrician schedule: Dade City 7,190
Pediatrician schedule: Dania Beach 21,477
Pediatrician schedule: Davie 91,729
Pediatrician schedule: Daytona Beach 63,795
Pediatrician schedule: De Bary 16,200


Eur. J. Lipid Sci. Technol. 2/2013
Effect of talc and water addition on olive oil quality and antioxidants
Fasting regulates FSP27 expression in the liver [Commentary]
Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice [Research Articles]
Association of Shiga toxin glycosphingolipid receptors with membrane microdomains of toxin-sensitive lymphoid and myeloid cells [Research Articles]
Novel common and rare genetic determinants of paraoxonase activity: FTO, SERPINA12, and ITGAL [Patient-Oriented and Epidemiological Research]
The combined effects of genetic variation in the SIRT1 gene and dietary intake of n-3 and n-6 polyunsaturated fatty acids on serum LDL-C and HDL-C levels: a population based study
Probing microscopic material properties inside simulated membranes through spatially resolved three-dimensional local pressure fields and surface tensions.
Differential effects of estrogen/androgen on the prevention of nonalcoholic fatty liver disease in the male rat [Research Articles]
Involvement of toll-like receptor 2 and 4 in association between dyslipidemia and osteoclast differentiation in apolipoprotein E deficient rat periodontium

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Enzymatic hydrolysis of palm stearin to produce diacylglycerol with a highly thermostable lipase

2013-02-15 22:44:00 (читать в оригинале)

AbstractThis paper firstly presents the production of diacylglycerol (DAG) by hydrolysis of high‐melting oil by a highly thermostable lipase (T1 lipase). T1 lipase was expressed in recombinant Escherichia coli, and used to produce diacylglycerol by catalyzing the hydrolysis of palm stearin. The optimal conditions were obtained by a water content of 30% (w/w, with respect to oil mass), T1 lipase at a concentration of 7.5 U/g (U/w, with respect to oil mass) and at 60oC. Scale‐up reaction was attempted based on the optimized conditions and 28.1% of DAG was achieved. Molecular distillation was employed for purification of DAG from the reaction mixture and the final DAG product yielded 42.5% of DAG (27.8% for 1,3‐DAG and 14.7 for 1,2‐DAG) and 57.5% of triacylglycerol (TAG). During hydr...







Pediatrician schedule: Boca Raton 83,280
Pediatrician schedule: Bonita Springs 42,874
Pediatrician schedule: Boyette 6,874
Pediatrician schedule: Boynton Beach 69,654
Pediatrician schedule: Bradenton 53,973
Pediatrician schedule: Brandon, FL 90,833
Pediatrician schedule: Brent, FL 22,845
Pediatrician schedule: Broadview Park 7,278
Pediatrician schedule: Brooksville, FL 8,267
Pediatrician schedule: Brownsville, FL 15,634
Pediatrician schedule: Butler Beach 6,265
Pediatrician schedule: Callaway, FL 13,972
Pediatrician schedule: Cantonment 44,893
Pediatrician schedule: Cape Canaveral 10,081
Pediatrician schedule: Cape Coral, FL 154,202
Pediatrician schedule: Carol City 64,569
Pediatrician schedule: Casselberry 24,792
Pediatrician schedule: Central Pasco 69,995
Pediatrician schedule: Central Volusia 24,310
Pediatrician schedule: Century Village 8,483
Pediatrician schedule: Cheval 8,864
Pediatrician schedule: Citrus Park 23,585
Pediatrician schedule: Citrus Park-Fern Lake, FL 117,103
Pediatrician schedule: Citrus Ridge 14,195
Pediatrician schedule: Clearwater, FL 106,081
Pediatrician schedule: Clermont, FL 13,252
Pediatrician schedule: Clewiston 7,107
Pediatrician schedule: Cocoa 16,538
Pediatrician schedule: Cocoa Beach 11,862
Pediatrician schedule: Cocoa West 7,806
Pediatrician schedule: Coconut Creek 50,544
Pediatrician schedule: Collier Manor-Cresthaven 8,287
Pediatrician schedule: Combee Settlement 6,422
Pediatrician schedule: Conway, FL 16,998
Pediatrician schedule: Cooper City 29,585
Pediatrician schedule: Coral Gables 44,425
Pediatrician schedule: Coral Springs, FL 126,518
Pediatrician schedule: Coral Terrace 26,482
Pediatrician schedule: Country Club, FL 39,441
Pediatrician schedule: Country Walk 11,571
Pediatrician schedule: Crestview, FL 19,868
Pediatrician schedule: Cutler Ridge 26,918
Pediatrician schedule: Cutler, FL 18,889
Pediatrician schedule: Cypress Gardens 10,449
Pediatrician schedule: Cypress Lake 15,915
Pediatrician schedule: Dade City 7,190
Pediatrician schedule: Dania Beach 21,477
Pediatrician schedule: Davie 91,729
Pediatrician schedule: Daytona Beach 63,795
Pediatrician schedule: De Bary 16,200


Lipid metabolism, immunity and metabolic diseases
The combined effects of genetic variation in the SIRT1 gene and dietary intake of n-3 and n-6 polyunsaturated fatty acids on serum LDL-C and HDL-C levels: a population based study
Probing microscopic material properties inside simulated membranes through spatially resolved three-dimensional local pressure fields and surface tensions.
Involvement of toll-like receptor 2 and 4 in association between dyslipidemia and osteoclast differentiation in apolipoprotein E deficient rat periodontium
A common variant highly associated with plasma VEGFA levels also contributes to the variation of both LDL-C and HDL-C [Patient-Oriented and Epidemiological Research]
Association of Shiga toxin glycosphingolipid receptors with membrane microdomains of toxin-sensitive lymphoid and myeloid cells [Research Articles]
Risk factors for cardiovascular disease: renewed interest in triglycerides
Differential effects of estrogen/androgen on the prevention of nonalcoholic fatty liver disease in the male rat [Research Articles]
Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice [Research Articles]
Fasting regulates FSP27 expression in the liver [Commentary]