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Australian families living with rare disease: experiences of diagnosis, health services use and needs for psychosocial support

2013-02-15 22:01:00 (читать в оригинале)

Conclusions:Australian families caring for children with genetic metabolic disorders are adversely impacted by delays in diagnosis, lack of easy access to peer support groups and lack of psychological support. Further research is needed to estimate economic impact and to analyse health service delivery models for children with rare diseases in Australia. (Source: Orphanet Journal of Rare Diseases)







pediatrician schedule: Oakhurst-North Fork 30,244
pediatrician schedule: Oakland, CA 409,184
pediatrician schedule: Oakley, CA 32,786
pediatrician schedule: Oceano 7,665
pediatrician schedule: Oceanside, CA 172,901
pediatrician schedule: Oildale 32,978
pediatrician schedule: Ojai 7,807
pediatrician schedule: Olivehurst 13,144
pediatrician schedule: Ontario, CA 171,602
pediatrician schedule: Opal Cliffs 6,313
pediatrician schedule: Orange Cove 10,668
pediatrician schedule: Orange, CA 136,990
pediatrician schedule: Orangevale 29,818
pediatrician schedule: Orcutt 28,881
pediatrician schedule: Orinda 18,686
pediatrician schedule: Orland, CA 7,234
pediatrician schedule: Orosi 8,262
pediatrician schedule: Oroville East 9,268
pediatrician schedule: Oroville, CA 14,660
pediatrician schedule: Oxnard, CA 187,535
pediatrician schedule: Pacific Grove 14,637
pediatrician schedule: Pacifica 37,987
pediatrician schedule: Palermo, CA 6,107
pediatrician schedule: Palm Desert 51,878
pediatrician schedule: Palm Springs, CA 48,184
pediatrician schedule: Palmdale, CA 143,985
pediatrician schedule: Palo Alto, CA 60,171
pediatrician schedule: Palomar-Julian 6,523
pediatrician schedule: Palos Verdes 91,593
pediatrician schedule: Palos Verdes Estates 13,546
pediatrician schedule: Paradise, CA 26,448
pediatrician schedule: Paramount 55,018
pediatrician schedule: Parkway-South Sacramento 42,859
pediatrician schedule: Parlier 13,331
pediatrician schedule: Pasadena, CA 143,667
pediatrician schedule: Paso Robles 42,751
pediatrician schedule: Patterson, CA 19,033
pediatrician schedule: Pauma Valley 7,475
pediatrician schedule: Pedley 14,778
pediatrician schedule: Pendleton, CA 38,073
pediatrician schedule: Perris 56,118
pediatrician schedule: Perris Valley, CA 190,588
pediatrician schedule: Petaluma 55,178
pediatrician schedule: Pico Rivera 62,895
pediatrician schedule: Piedmont, CA 10,572
pediatrician schedule: Pine Grove-Silver Lake 10,703
pediatrician schedule: Pinole 18,939
pediatrician schedule: Pismo Beach 8,640
pediatrician schedule: Pittsburg, CA 65,129
pediatrician schedule: Placentia 49,938
pediatrician schedule: Placerville 10,095
pediatrician schedule: Pleasant Hill, CA 33,073
pediatrician schedule: Pleasanton, CA 67,543
pediatrician schedule: Pomona, CA 152,367
pediatrician schedule: Port Hueneme 21,555
pediatrician schedule: Porterville 44,726
pediatrician schedule: Portola Hills 6,618
pediatrician schedule: Poway 49,881
pediatrician schedule: Prunedale 16,393
pediatrician schedule: Quartz Hill 10,089
pediatrician schedule: Ramona, CA 16,527
pediatrician schedule: Rancho Cordova 62,939
pediatrician schedule: Rancho Cucamonga, CA 171,809
pediatrician schedule: Rancho Mirage 16,800
pediatrician schedule: Rancho Palos Verdes 40,964
pediatrician schedule: Rancho San Diego 21,229
pediatrician schedule: Rancho Santa Margarita 49,458
pediatrician schedule: Red Bluff 13,795
pediatrician schedule: Redding, CA 90,521
pediatrician schedule: Redlands, CA 69,976
pediatrician schedule: Redondo Beach 66,711
pediatrician schedule: Redwood City 74,508
pediatrician schedule: Redwood-Potter 11,545
pediatrician schedule: Reedley 23,620
pediatrician schedule: Rialto 98,702
pediatrician schedule: Richmond, CA 103,166
pediatrician schedule: Ridgecrest, CA 25,895
pediatrician schedule: Rio del Mar 8,992
pediatrician schedule: Rio Linda 11,686
pediatrician schedule: Rio Vista, CA 7,922
pediatrician schedule: Ripon, CA 14,738
pediatrician schedule: Riverbank 20,684
pediatrician schedule: Riverside, CA 297,859
pediatrician schedule: Rocklin 53,572
pediatrician schedule: Rodeo 9,241
pediatrician schedule: Rohnert Park 40,921
pediatrician schedule: Rolling Hills Estates 7,834
pediatrician schedule: Rosamond 16,970
pediatrician schedule: Rosedale, CA 9,987
pediatrician schedule: Roseland, CA 6,383
pediatrician schedule: Rosemead 54,272
pediatrician schedule: Rosemont, CA 25,574
pediatrician schedule: Roseville, CA 115,687
pediatrician schedule: Ross Valley 59,297
pediatrician schedule: Rossmoor, CA 10,664
pediatrician schedule: Rowland Heights 49,530
pediatrician schedule: Rubidoux 38,478
pediatrician schedule: Russian River-Coastal 24,878
pediatrician schedule: Sacramento, CA 466,687
pediatrician schedule: Salida, CA 14,143
pediatrician schedule: Salinas, CA 144,276
pediatrician schedule: San Anselmo 12,058
pediatrician schedule: San Bernardino, CA 198,410
pediatrician schedule: San Bruno 41,415
pediatrician schedule: San Buenaventura (Ventura), CA 104,423
pediatrician schedule: San Carlos, CA 27,424
pediatrician schedule: San Clemente 61,610
pediatrician schedule: San Diego Country Estates 9,755
pediatrician schedule: San Diego, CA 1,306,301

The role of CCAAT enhancer‐binding protein homologous protein in human immunodeficiency virus protease‐inhibitor–induced hepatic lipotoxicity in mice
Erythropoietin-directed erythropoiesis depends on serpin inhibition of erythroblast lysosomal cathepsins
Paget's Disease of Bone
Notch pathway activation targets AML-initiating cell homeostasis and differentiation
DTB: Tinnitus

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Is Gun Violence A Public Health Issue Requiring Physician Intervention?

2013-02-15 22:01:00 (читать в оригинале)

Recent violent events have driven gun policy to the top of the President's second-term agenda. In an article being published early online in Annals of Internal Medicine, public health experts at the Johns Hopkins Center for Gun Policy and Research call for greater physician involvement in the current gun policy dialogue. The authors cite grim statistics regarding gun violence and survival rates and conclude that greater emphasis needs to be placed on prevention. Physicians are uniquely poised to be at the forefront of prevention efforts... (Source: Health News from Medical News Today)







pediatrician schedule: Oakhurst-North Fork 30,244
pediatrician schedule: Oakland, CA 409,184
pediatrician schedule: Oakley, CA 32,786
pediatrician schedule: Oceano 7,665
pediatrician schedule: Oceanside, CA 172,901
pediatrician schedule: Oildale 32,978
pediatrician schedule: Ojai 7,807
pediatrician schedule: Olivehurst 13,144
pediatrician schedule: Ontario, CA 171,602
pediatrician schedule: Opal Cliffs 6,313
pediatrician schedule: Orange Cove 10,668
pediatrician schedule: Orange, CA 136,990
pediatrician schedule: Orangevale 29,818
pediatrician schedule: Orcutt 28,881
pediatrician schedule: Orinda 18,686
pediatrician schedule: Orland, CA 7,234
pediatrician schedule: Orosi 8,262
pediatrician schedule: Oroville East 9,268
pediatrician schedule: Oroville, CA 14,660
pediatrician schedule: Oxnard, CA 187,535
pediatrician schedule: Pacific Grove 14,637
pediatrician schedule: Pacifica 37,987
pediatrician schedule: Palermo, CA 6,107
pediatrician schedule: Palm Desert 51,878
pediatrician schedule: Palm Springs, CA 48,184
pediatrician schedule: Palmdale, CA 143,985
pediatrician schedule: Palo Alto, CA 60,171
pediatrician schedule: Palomar-Julian 6,523
pediatrician schedule: Palos Verdes 91,593
pediatrician schedule: Palos Verdes Estates 13,546
pediatrician schedule: Paradise, CA 26,448
pediatrician schedule: Paramount 55,018
pediatrician schedule: Parkway-South Sacramento 42,859
pediatrician schedule: Parlier 13,331
pediatrician schedule: Pasadena, CA 143,667
pediatrician schedule: Paso Robles 42,751
pediatrician schedule: Patterson, CA 19,033
pediatrician schedule: Pauma Valley 7,475
pediatrician schedule: Pedley 14,778
pediatrician schedule: Pendleton, CA 38,073
pediatrician schedule: Perris 56,118
pediatrician schedule: Perris Valley, CA 190,588
pediatrician schedule: Petaluma 55,178
pediatrician schedule: Pico Rivera 62,895
pediatrician schedule: Piedmont, CA 10,572
pediatrician schedule: Pine Grove-Silver Lake 10,703
pediatrician schedule: Pinole 18,939
pediatrician schedule: Pismo Beach 8,640
pediatrician schedule: Pittsburg, CA 65,129
pediatrician schedule: Placentia 49,938
pediatrician schedule: Placerville 10,095
pediatrician schedule: Pleasant Hill, CA 33,073
pediatrician schedule: Pleasanton, CA 67,543
pediatrician schedule: Pomona, CA 152,367
pediatrician schedule: Port Hueneme 21,555
pediatrician schedule: Porterville 44,726
pediatrician schedule: Portola Hills 6,618
pediatrician schedule: Poway 49,881
pediatrician schedule: Prunedale 16,393
pediatrician schedule: Quartz Hill 10,089
pediatrician schedule: Ramona, CA 16,527
pediatrician schedule: Rancho Cordova 62,939
pediatrician schedule: Rancho Cucamonga, CA 171,809
pediatrician schedule: Rancho Mirage 16,800
pediatrician schedule: Rancho Palos Verdes 40,964
pediatrician schedule: Rancho San Diego 21,229
pediatrician schedule: Rancho Santa Margarita 49,458
pediatrician schedule: Red Bluff 13,795
pediatrician schedule: Redding, CA 90,521
pediatrician schedule: Redlands, CA 69,976
pediatrician schedule: Redondo Beach 66,711
pediatrician schedule: Redwood City 74,508
pediatrician schedule: Redwood-Potter 11,545
pediatrician schedule: Reedley 23,620
pediatrician schedule: Rialto 98,702
pediatrician schedule: Richmond, CA 103,166
pediatrician schedule: Ridgecrest, CA 25,895
pediatrician schedule: Rio del Mar 8,992
pediatrician schedule: Rio Linda 11,686
pediatrician schedule: Rio Vista, CA 7,922
pediatrician schedule: Ripon, CA 14,738
pediatrician schedule: Riverbank 20,684
pediatrician schedule: Riverside, CA 297,859
pediatrician schedule: Rocklin 53,572
pediatrician schedule: Rodeo 9,241
pediatrician schedule: Rohnert Park 40,921
pediatrician schedule: Rolling Hills Estates 7,834
pediatrician schedule: Rosamond 16,970
pediatrician schedule: Rosedale, CA 9,987
pediatrician schedule: Roseland, CA 6,383
pediatrician schedule: Rosemead 54,272
pediatrician schedule: Rosemont, CA 25,574
pediatrician schedule: Roseville, CA 115,687
pediatrician schedule: Ross Valley 59,297
pediatrician schedule: Rossmoor, CA 10,664
pediatrician schedule: Rowland Heights 49,530
pediatrician schedule: Rubidoux 38,478
pediatrician schedule: Russian River-Coastal 24,878
pediatrician schedule: Sacramento, CA 466,687
pediatrician schedule: Salida, CA 14,143
pediatrician schedule: Salinas, CA 144,276
pediatrician schedule: San Anselmo 12,058
pediatrician schedule: San Bernardino, CA 198,410
pediatrician schedule: San Bruno 41,415
pediatrician schedule: San Buenaventura (Ventura), CA 104,423
pediatrician schedule: San Carlos, CA 27,424
pediatrician schedule: San Clemente 61,610
pediatrician schedule: San Diego Country Estates 9,755
pediatrician schedule: San Diego, CA 1,306,301

Urgency, incontinence and other urinary issues … why bother?
Erratum
The role of CCAAT enhancer‐binding protein homologous protein in human immunodeficiency virus protease‐inhibitor–induced hepatic lipotoxicity in mice
Sodium vanadate combined with L-ascorbic acid delays disease progression, enhances motor performance, and ameliorates muscle atrophy and weakness in mice with spinal muscular atrophy
New Resource: Pocket Guide to Diagnostic Tests, 6e
Pocket Guide to Diagnostic Tests, 6e is a quick reference guide to the selection and interpretation of more than 450 commonly used diagnostic tests.

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Vitamin D supplement labels may be inaccurate (Reuters, 13 February 2013)

2013-02-15 22:01:00 (читать в оригинале)

The levels of vitamin D found in supplements may vary signficantly from the amount stated on the label. The findings were published in JAMA Internal Medicine. Full article (Source: Society for Endocrinology)







pediatrician schedule: Oakhurst-North Fork 30,244
pediatrician schedule: Oakland, CA 409,184
pediatrician schedule: Oakley, CA 32,786
pediatrician schedule: Oceano 7,665
pediatrician schedule: Oceanside, CA 172,901
pediatrician schedule: Oildale 32,978
pediatrician schedule: Ojai 7,807
pediatrician schedule: Olivehurst 13,144
pediatrician schedule: Ontario, CA 171,602
pediatrician schedule: Opal Cliffs 6,313
pediatrician schedule: Orange Cove 10,668
pediatrician schedule: Orange, CA 136,990
pediatrician schedule: Orangevale 29,818
pediatrician schedule: Orcutt 28,881
pediatrician schedule: Orinda 18,686
pediatrician schedule: Orland, CA 7,234
pediatrician schedule: Orosi 8,262
pediatrician schedule: Oroville East 9,268
pediatrician schedule: Oroville, CA 14,660
pediatrician schedule: Oxnard, CA 187,535
pediatrician schedule: Pacific Grove 14,637
pediatrician schedule: Pacifica 37,987
pediatrician schedule: Palermo, CA 6,107
pediatrician schedule: Palm Desert 51,878
pediatrician schedule: Palm Springs, CA 48,184
pediatrician schedule: Palmdale, CA 143,985
pediatrician schedule: Palo Alto, CA 60,171
pediatrician schedule: Palomar-Julian 6,523
pediatrician schedule: Palos Verdes 91,593
pediatrician schedule: Palos Verdes Estates 13,546
pediatrician schedule: Paradise, CA 26,448
pediatrician schedule: Paramount 55,018
pediatrician schedule: Parkway-South Sacramento 42,859
pediatrician schedule: Parlier 13,331
pediatrician schedule: Pasadena, CA 143,667
pediatrician schedule: Paso Robles 42,751
pediatrician schedule: Patterson, CA 19,033
pediatrician schedule: Pauma Valley 7,475
pediatrician schedule: Pedley 14,778
pediatrician schedule: Pendleton, CA 38,073
pediatrician schedule: Perris 56,118
pediatrician schedule: Perris Valley, CA 190,588
pediatrician schedule: Petaluma 55,178
pediatrician schedule: Pico Rivera 62,895
pediatrician schedule: Piedmont, CA 10,572
pediatrician schedule: Pine Grove-Silver Lake 10,703
pediatrician schedule: Pinole 18,939
pediatrician schedule: Pismo Beach 8,640
pediatrician schedule: Pittsburg, CA 65,129
pediatrician schedule: Placentia 49,938
pediatrician schedule: Placerville 10,095
pediatrician schedule: Pleasant Hill, CA 33,073
pediatrician schedule: Pleasanton, CA 67,543
pediatrician schedule: Pomona, CA 152,367
pediatrician schedule: Port Hueneme 21,555
pediatrician schedule: Porterville 44,726
pediatrician schedule: Portola Hills 6,618
pediatrician schedule: Poway 49,881
pediatrician schedule: Prunedale 16,393
pediatrician schedule: Quartz Hill 10,089
pediatrician schedule: Ramona, CA 16,527
pediatrician schedule: Rancho Cordova 62,939
pediatrician schedule: Rancho Cucamonga, CA 171,809
pediatrician schedule: Rancho Mirage 16,800
pediatrician schedule: Rancho Palos Verdes 40,964
pediatrician schedule: Rancho San Diego 21,229
pediatrician schedule: Rancho Santa Margarita 49,458
pediatrician schedule: Red Bluff 13,795
pediatrician schedule: Redding, CA 90,521
pediatrician schedule: Redlands, CA 69,976
pediatrician schedule: Redondo Beach 66,711
pediatrician schedule: Redwood City 74,508
pediatrician schedule: Redwood-Potter 11,545
pediatrician schedule: Reedley 23,620
pediatrician schedule: Rialto 98,702
pediatrician schedule: Richmond, CA 103,166
pediatrician schedule: Ridgecrest, CA 25,895
pediatrician schedule: Rio del Mar 8,992
pediatrician schedule: Rio Linda 11,686
pediatrician schedule: Rio Vista, CA 7,922
pediatrician schedule: Ripon, CA 14,738
pediatrician schedule: Riverbank 20,684
pediatrician schedule: Riverside, CA 297,859
pediatrician schedule: Rocklin 53,572
pediatrician schedule: Rodeo 9,241
pediatrician schedule: Rohnert Park 40,921
pediatrician schedule: Rolling Hills Estates 7,834
pediatrician schedule: Rosamond 16,970
pediatrician schedule: Rosedale, CA 9,987
pediatrician schedule: Roseland, CA 6,383
pediatrician schedule: Rosemead 54,272
pediatrician schedule: Rosemont, CA 25,574
pediatrician schedule: Roseville, CA 115,687
pediatrician schedule: Ross Valley 59,297
pediatrician schedule: Rossmoor, CA 10,664
pediatrician schedule: Rowland Heights 49,530
pediatrician schedule: Rubidoux 38,478
pediatrician schedule: Russian River-Coastal 24,878
pediatrician schedule: Sacramento, CA 466,687
pediatrician schedule: Salida, CA 14,143
pediatrician schedule: Salinas, CA 144,276
pediatrician schedule: San Anselmo 12,058
pediatrician schedule: San Bernardino, CA 198,410
pediatrician schedule: San Bruno 41,415
pediatrician schedule: San Buenaventura (Ventura), CA 104,423
pediatrician schedule: San Carlos, CA 27,424
pediatrician schedule: San Clemente 61,610
pediatrician schedule: San Diego Country Estates 9,755
pediatrician schedule: San Diego, CA 1,306,301

Sodium vanadate combined with L-ascorbic acid delays disease progression, enhances motor performance, and ameliorates muscle atrophy and weakness in mice with spinal muscular atrophy
Annals of Internal Medicine tip sheet for Feb. 12, 2013
Inflammatory status in obesity: emergent predictors
Erratum
Neutrophils control the magnitude and spread of the immune response in a thromboxane A2-mediated process

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Interventions for treating persistent and intractable hiccups in adults

2013-02-15 22:00:00 (читать в оригинале)

The objective of this review was to evaluate the effectiveness of pharmacological and non-pharmacological interventions used in the treatment of persistent and intractable hiccups of any aetiology in adults.   Search methods Studies were identified from the following databases: CENTRAL, CDSR, DARE, MEDLINE, EMBASE, CINAHL, PsychINFO and SIGLE (last search March 2012). The search strategy for all the databases searched was based on the MEDLINE search strategy presented in Appendix 1. ... (Source: NeLM - Disease Focused Reviews)







pediatrician schedule: Oakhurst-North Fork 30,244
pediatrician schedule: Oakland, CA 409,184
pediatrician schedule: Oakley, CA 32,786
pediatrician schedule: Oceano 7,665
pediatrician schedule: Oceanside, CA 172,901
pediatrician schedule: Oildale 32,978
pediatrician schedule: Ojai 7,807
pediatrician schedule: Olivehurst 13,144
pediatrician schedule: Ontario, CA 171,602
pediatrician schedule: Opal Cliffs 6,313
pediatrician schedule: Orange Cove 10,668
pediatrician schedule: Orange, CA 136,990
pediatrician schedule: Orangevale 29,818
pediatrician schedule: Orcutt 28,881
pediatrician schedule: Orinda 18,686
pediatrician schedule: Orland, CA 7,234
pediatrician schedule: Orosi 8,262
pediatrician schedule: Oroville East 9,268
pediatrician schedule: Oroville, CA 14,660
pediatrician schedule: Oxnard, CA 187,535
pediatrician schedule: Pacific Grove 14,637
pediatrician schedule: Pacifica 37,987
pediatrician schedule: Palermo, CA 6,107
pediatrician schedule: Palm Desert 51,878
pediatrician schedule: Palm Springs, CA 48,184
pediatrician schedule: Palmdale, CA 143,985
pediatrician schedule: Palo Alto, CA 60,171
pediatrician schedule: Palomar-Julian 6,523
pediatrician schedule: Palos Verdes 91,593
pediatrician schedule: Palos Verdes Estates 13,546
pediatrician schedule: Paradise, CA 26,448
pediatrician schedule: Paramount 55,018
pediatrician schedule: Parkway-South Sacramento 42,859
pediatrician schedule: Parlier 13,331
pediatrician schedule: Pasadena, CA 143,667
pediatrician schedule: Paso Robles 42,751
pediatrician schedule: Patterson, CA 19,033
pediatrician schedule: Pauma Valley 7,475
pediatrician schedule: Pedley 14,778
pediatrician schedule: Pendleton, CA 38,073
pediatrician schedule: Perris 56,118
pediatrician schedule: Perris Valley, CA 190,588
pediatrician schedule: Petaluma 55,178
pediatrician schedule: Pico Rivera 62,895
pediatrician schedule: Piedmont, CA 10,572
pediatrician schedule: Pine Grove-Silver Lake 10,703
pediatrician schedule: Pinole 18,939
pediatrician schedule: Pismo Beach 8,640
pediatrician schedule: Pittsburg, CA 65,129
pediatrician schedule: Placentia 49,938
pediatrician schedule: Placerville 10,095
pediatrician schedule: Pleasant Hill, CA 33,073
pediatrician schedule: Pleasanton, CA 67,543
pediatrician schedule: Pomona, CA 152,367
pediatrician schedule: Port Hueneme 21,555
pediatrician schedule: Porterville 44,726
pediatrician schedule: Portola Hills 6,618
pediatrician schedule: Poway 49,881
pediatrician schedule: Prunedale 16,393
pediatrician schedule: Quartz Hill 10,089
pediatrician schedule: Ramona, CA 16,527
pediatrician schedule: Rancho Cordova 62,939
pediatrician schedule: Rancho Cucamonga, CA 171,809
pediatrician schedule: Rancho Mirage 16,800
pediatrician schedule: Rancho Palos Verdes 40,964
pediatrician schedule: Rancho San Diego 21,229
pediatrician schedule: Rancho Santa Margarita 49,458
pediatrician schedule: Red Bluff 13,795
pediatrician schedule: Redding, CA 90,521
pediatrician schedule: Redlands, CA 69,976
pediatrician schedule: Redondo Beach 66,711
pediatrician schedule: Redwood City 74,508
pediatrician schedule: Redwood-Potter 11,545
pediatrician schedule: Reedley 23,620
pediatrician schedule: Rialto 98,702
pediatrician schedule: Richmond, CA 103,166
pediatrician schedule: Ridgecrest, CA 25,895
pediatrician schedule: Rio del Mar 8,992
pediatrician schedule: Rio Linda 11,686
pediatrician schedule: Rio Vista, CA 7,922
pediatrician schedule: Ripon, CA 14,738
pediatrician schedule: Riverbank 20,684
pediatrician schedule: Riverside, CA 297,859
pediatrician schedule: Rocklin 53,572
pediatrician schedule: Rodeo 9,241
pediatrician schedule: Rohnert Park 40,921
pediatrician schedule: Rolling Hills Estates 7,834
pediatrician schedule: Rosamond 16,970
pediatrician schedule: Rosedale, CA 9,987
pediatrician schedule: Roseland, CA 6,383
pediatrician schedule: Rosemead 54,272
pediatrician schedule: Rosemont, CA 25,574
pediatrician schedule: Roseville, CA 115,687
pediatrician schedule: Ross Valley 59,297
pediatrician schedule: Rossmoor, CA 10,664
pediatrician schedule: Rowland Heights 49,530
pediatrician schedule: Rubidoux 38,478
pediatrician schedule: Russian River-Coastal 24,878
pediatrician schedule: Sacramento, CA 466,687
pediatrician schedule: Salida, CA 14,143
pediatrician schedule: Salinas, CA 144,276
pediatrician schedule: San Anselmo 12,058
pediatrician schedule: San Bernardino, CA 198,410
pediatrician schedule: San Bruno 41,415
pediatrician schedule: San Buenaventura (Ventura), CA 104,423
pediatrician schedule: San Carlos, CA 27,424
pediatrician schedule: San Clemente 61,610
pediatrician schedule: San Diego Country Estates 9,755
pediatrician schedule: San Diego, CA 1,306,301

Anemia during treatment with peginterferon Alfa‐2b/ribavirin and boceprevir: Analysis from the serine protease inhibitor therapy 2 (SPRINT‐2) trial
Emergency Department Crowding May Be Associated With Acute Coronary Syndrome-Induced Post-Traumatic Stress Disorder Symptoms
Systematic review of central nervous system anomalies in incontinentia pigmenti
TIE2‐expressing monocytes as a diagnostic marker for hepatocellular carcinoma correlates with angiogenesis
Annals of Internal Medicine tip sheet for Feb. 12, 2013

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Iron uptake controls the generation of Leishmania infective forms through regulation of ROS levels

2013-02-15 22:00:00 (читать в оригинале)

During its life cycle, Leishmania undergoes extreme environmental changes, alternating between insect vectors and vertebrate hosts. Elevated temperature and decreased pH, conditions encountered after macrophage invasion, can induce axenic differentiation of avirulent promastigotes into virulent amastigotes. Here we show that iron uptake is a major trigger for the differentiation of Leishmania amazonensis amastigotes, independently of temperature and pH changes. We found that iron depletion from the culture medium triggered expression of the ferrous iron transporter LIT1 (Leishmania iron transporter 1), an increase in iron content of the parasites, growth arrest, and differentiation of wild-type (WT) promastigotes into infective amastigotes. In contrast, LIT1-null promastigotes showed reduc...







pediatrician schedule: Oakhurst-North Fork 30,244
pediatrician schedule: Oakland, CA 409,184
pediatrician schedule: Oakley, CA 32,786
pediatrician schedule: Oceano 7,665
pediatrician schedule: Oceanside, CA 172,901
pediatrician schedule: Oildale 32,978
pediatrician schedule: Ojai 7,807
pediatrician schedule: Olivehurst 13,144
pediatrician schedule: Ontario, CA 171,602
pediatrician schedule: Opal Cliffs 6,313
pediatrician schedule: Orange Cove 10,668
pediatrician schedule: Orange, CA 136,990
pediatrician schedule: Orangevale 29,818
pediatrician schedule: Orcutt 28,881
pediatrician schedule: Orinda 18,686
pediatrician schedule: Orland, CA 7,234
pediatrician schedule: Orosi 8,262
pediatrician schedule: Oroville East 9,268
pediatrician schedule: Oroville, CA 14,660
pediatrician schedule: Oxnard, CA 187,535
pediatrician schedule: Pacific Grove 14,637
pediatrician schedule: Pacifica 37,987
pediatrician schedule: Palermo, CA 6,107
pediatrician schedule: Palm Desert 51,878
pediatrician schedule: Palm Springs, CA 48,184
pediatrician schedule: Palmdale, CA 143,985
pediatrician schedule: Palo Alto, CA 60,171
pediatrician schedule: Palomar-Julian 6,523
pediatrician schedule: Palos Verdes 91,593
pediatrician schedule: Palos Verdes Estates 13,546
pediatrician schedule: Paradise, CA 26,448
pediatrician schedule: Paramount 55,018
pediatrician schedule: Parkway-South Sacramento 42,859
pediatrician schedule: Parlier 13,331
pediatrician schedule: Pasadena, CA 143,667
pediatrician schedule: Paso Robles 42,751
pediatrician schedule: Patterson, CA 19,033
pediatrician schedule: Pauma Valley 7,475
pediatrician schedule: Pedley 14,778
pediatrician schedule: Pendleton, CA 38,073
pediatrician schedule: Perris 56,118
pediatrician schedule: Perris Valley, CA 190,588
pediatrician schedule: Petaluma 55,178
pediatrician schedule: Pico Rivera 62,895
pediatrician schedule: Piedmont, CA 10,572
pediatrician schedule: Pine Grove-Silver Lake 10,703
pediatrician schedule: Pinole 18,939
pediatrician schedule: Pismo Beach 8,640
pediatrician schedule: Pittsburg, CA 65,129
pediatrician schedule: Placentia 49,938
pediatrician schedule: Placerville 10,095
pediatrician schedule: Pleasant Hill, CA 33,073
pediatrician schedule: Pleasanton, CA 67,543
pediatrician schedule: Pomona, CA 152,367
pediatrician schedule: Port Hueneme 21,555
pediatrician schedule: Porterville 44,726
pediatrician schedule: Portola Hills 6,618
pediatrician schedule: Poway 49,881
pediatrician schedule: Prunedale 16,393
pediatrician schedule: Quartz Hill 10,089
pediatrician schedule: Ramona, CA 16,527
pediatrician schedule: Rancho Cordova 62,939
pediatrician schedule: Rancho Cucamonga, CA 171,809
pediatrician schedule: Rancho Mirage 16,800
pediatrician schedule: Rancho Palos Verdes 40,964
pediatrician schedule: Rancho San Diego 21,229
pediatrician schedule: Rancho Santa Margarita 49,458
pediatrician schedule: Red Bluff 13,795
pediatrician schedule: Redding, CA 90,521
pediatrician schedule: Redlands, CA 69,976
pediatrician schedule: Redondo Beach 66,711
pediatrician schedule: Redwood City 74,508
pediatrician schedule: Redwood-Potter 11,545
pediatrician schedule: Reedley 23,620
pediatrician schedule: Rialto 98,702
pediatrician schedule: Richmond, CA 103,166
pediatrician schedule: Ridgecrest, CA 25,895
pediatrician schedule: Rio del Mar 8,992
pediatrician schedule: Rio Linda 11,686
pediatrician schedule: Rio Vista, CA 7,922
pediatrician schedule: Ripon, CA 14,738
pediatrician schedule: Riverbank 20,684
pediatrician schedule: Riverside, CA 297,859
pediatrician schedule: Rocklin 53,572
pediatrician schedule: Rodeo 9,241
pediatrician schedule: Rohnert Park 40,921
pediatrician schedule: Rolling Hills Estates 7,834
pediatrician schedule: Rosamond 16,970
pediatrician schedule: Rosedale, CA 9,987
pediatrician schedule: Roseland, CA 6,383
pediatrician schedule: Rosemead 54,272
pediatrician schedule: Rosemont, CA 25,574
pediatrician schedule: Roseville, CA 115,687
pediatrician schedule: Ross Valley 59,297
pediatrician schedule: Rossmoor, CA 10,664
pediatrician schedule: Rowland Heights 49,530
pediatrician schedule: Rubidoux 38,478
pediatrician schedule: Russian River-Coastal 24,878
pediatrician schedule: Sacramento, CA 466,687
pediatrician schedule: Salida, CA 14,143
pediatrician schedule: Salinas, CA 144,276
pediatrician schedule: San Anselmo 12,058
pediatrician schedule: San Bernardino, CA 198,410
pediatrician schedule: San Bruno 41,415
pediatrician schedule: San Buenaventura (Ventura), CA 104,423
pediatrician schedule: San Carlos, CA 27,424
pediatrician schedule: San Clemente 61,610
pediatrician schedule: San Diego Country Estates 9,755
pediatrician schedule: San Diego, CA 1,306,301

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